July 5, 2024

Mercedes-Benz S-Class W221 (2005-2013) – Fuse box

Arnold019 mins

Mercedes-Benz S-Class w221 (2005-2013) – fuse box diagram

Year of manufacture: 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013.

Lighter fuse (electrical outlet) in Mercedes S-Class w221 (2005-2013). Is fuse 43 in the fuse box in the engine compartment

Fuse box in the engine compartment

Mercedes-Benz S – w221 – fuse box diagram – engine compartment
No. Description Amps [A]
20 Valid for motors 629, 642, 651:

CDI control unit;

Valid for 156, 157, 272, 273, 275, 276, 278 engines:

ME-SFI control unit [ME].

 10
21 Valid for 156, 157, 272, 273, 275, 276, 278 engines:

Terminal 87 of connection sleeve M1 i;

Valid for model 221 with motor 629 and motor 642:

CDI control unit;

Fuel pump relay;

Applies to the 221 model with 651 engine:

Valve quantity control.

 20
22 Applies to motors 156, 157, 272, 273, 276, 278:

Bushing for compass connector 87.

 15
23 until 2008:

Caliper connection bushing 87;
Applies to motor 275 (model 216):

Bushing for terminal connector 87 M1 i;
Valid for motor 273 (model 216):

Terminal connector sleeve 87 M2e;
Valid for motor 272, 273 (221 model):

87M2i Bushing compression fitting;
Applies to the 642 engine:

Bushing for compass connector 87;
from 2009 ..:
Valid for engine 156, 157, 272, 273, 275, 276, 278:

Bushing for compass connector 87;
Applies to model 221 with motor 629 and motor 642:

Bushing for compass connector 87;
Valid for 156, 157, 272, 273, 276, 278 motor:

87M2e caliper link bushing;
Valid for 275 engine:

87 M2i caliper link bushing;
Valid for model 221 with motor 629 and motor 642:

Bushing for compass connector 87;
Applies to model 221 with 651 engine:

Rear SAM control unit with fuse and relay module.

 20
24 Valid for engines 157, 272, 273, 276, 278:

87M1e D terminal connection bushing;

Applies to Engine 642:

CDI control unit.

 25
25 Instrument cluster 7,5
26 Front left light assembly 10
27 Right Front Light Assembly 10
28 Valid for engine 275:

EGS control unit;
Valid without motor 275: W

Fully integrated gearbox control unit (VGS).

 7,5
29 Rear SAM control unit with fuse and relay module 5
30 Valid for motors 629, 642, 651:

CDI control unit;

Applies to 156, 157, 272, 273, 275, 276, 278 engines:

ME-SFI control unit [ME];

Fuel pump control unit.

 7,5
31 S400 Hybrid:

Electric refrigerant compressor.

 5
32 Applies to model with ECO start/stop function:

Controller for additional transmission oil pump;

S 400 Hybrid:

Controller for additional transmission oil pump.

 15
33 Valid as of 1.9.10 without the S 400 Hybrid model:

ESP control unit;

S 400 Hybrid:

Battery management system control unit;

DC/DC converter control unit;

Power electronics control unit.

 5
34 S 400 Hybrid:

Brake control unit with energy recuperation

 5
35 Electric Parking Brake Controller 5
36 Data Link Connector (pin 16) 10
37 To CIS control unit 7,5
38 Central gate control unit 7,5
39 Instrument cluster 7,5
40 Upper control panel control unit 7,5
41 Lower wiper motor 30
42 Main wiper motor 30
43 Front cigarette lighter with ashtray lighting 15
44 – –
45 S 400 Hybrid: electronic circulation pump 1 5
46 W221 with active body control (ABC), model 216:

ABC;

W221 without Active Body Control (ABC):

AIRmatic with ADS.

 15
47 SAM front control unit with fuse and relay module;

Steering column lift and lowering motor.

 15
48 until 2008:

SAM front control unit with fuse and relay module;

2009 onwards:

Motor to raise and lower the steering column.

 15
49 Steering column module 10
50 AAC Control Unit [KLA] 15
51 until 2008:

COMAND Screen

7,5
as of 2009:

COMMAND View;

SPLITVIEW.

 5
52 A W221:

Left horn;

Right horn.

 15
52 B W221, C216:

Left horn;

Right horn.

 15
53 – –
54 AC recirculation unit 40
55 Applies to the gasoline engine:

Electric air pump

 60
56 W221 without Active Body Control (ABC):

AIRmatic Compressor

 40
57 by 2008:

Windshield Wiper Parking Heater

 40
as of 2009:

Windshield Wiper Parking Heater

 30
60 as of 2009:

Electro-hydraulic power steering

 5
61 C216; W221 – from 2009 ..:

Control unit for restraint systems

 7,5
W221; until 2008:

Containment system control unit

 10
62 Night View Assist control unit 5
63 Valid for model 221 with engine 629 and engine 642 as of 1.9.08:

Fuel filter condensation sensor with heating element

 15
64 W221 as of 1.9.06:

NECK-PRO driver’s headrest solenoid;

NECK-PRO passenger head restraint solenoid.

 7,5
W221 from ’09:

NECK-PRO driver’s headrest solenoid;

NECK-PRO passenger head restraint solenoid.

 10
65 Effective 1.6.09:

12 V connector in the glove box

 15
66 DTR control unit (Distronic or Distronic Plus) 7,5
Relay
A Air Pump Relay
B Air Suspension Compressor Relay
C Relay 87, engine
D Terminal 15 relay
E Terminal 87 relay, chassis
F Horn relay
G Terminal 15R Relay
H Relay circuit 50, starter
J Relay circuit 15, starter
K. Windshield Wiper Parking Heater Relay

Left instrument panel fuse box

Mercedes-Benz S w221 – fuse box diagram – instrument panel left
No. Description Amps [A]
92 Left front seat control unit 40
93 Control unit for restraint systems;

US version:

Weight sensing system (WSS) control unit.

 7,5
94 as of 2009:

Multifunction camera.

 5
95 – –
96 Control unit of the tire pressure monitor [RDK] 5
97 W221:

Audio/video controller control unit (rear entertainment system).

 7,5
98 Rear entertainment system:

DVD player (from 2009).

 7,5
99 from 2009 onwards:

COMMAND view;

SPLITVIEW.

 7,5
100 from 2009 onwards:

Multimedia Interface Control Unit

 5
101 Rear entertainment system:

Left rear display;

Right rear display.

 10
102 Controller for the right front seat 40
103 ESP Control Unit 7,5
104 Audio Tuner Control Unit 40
105 – –
106 Japanese version:

Electronic Toll Control Unit (ETC);

Effective in South Korea as of 1.9.10:

TV/tuner connector ;

Refers to Navigation; from 2009:

Navigation Processor.

 1
107 SDAR (SIRIUS satellite radio) control unit (W221 of 2009);

Radio cyfrowe:

Digital audio broadcasting control unit;

HD Radio:

HD tuner control unit.

 5
108 W221:

Rear air conditioning control unit

 5
109 W221:

Rear blower middle connector

 15
110 W221:

Multicontour left rear seatback control;

Controller for multicontour right rear backrest.

 7,5
111 Multi-contour rear seat or rear entertainment system (model 221):

RCP control unit [HBF]

 5
112 W221; until 2008:

Left front door controller;

Right front door controller;

S 400 Hybrid:

SAM front control module with fuse and relay module.

 5
113 S 400 Hybrid:

DC/DC converter control unit

 5
See also  Mercedes-Benz A-Class w176 (2012-2018) - fuse box

Instrument panel fuse box on the right

Mercedes-Benz S w221 – fuse box diagram – right instrument panel
No. Description Amps [A]
70 C216:

Right door controller;

W221:

Right front door controller.

 40
71 Keyless Go Control Unit 15
72 S 400 Hybrid:

Pyrotechnic separator

 7,5
73 Japanese version:

COMMAND Controller;

TELE AID emergency call system (as of 2009):

Control unit for the emergency call system.

 5
74 TLC control unit [HDS] (remote trunk locking) 30
75 S 400 Hybrid:

Battery management system control unit;

Power electronics control unit.

 10
76 S 400 Hybrid:

Vacuum pump relay (+)

 15
Valid for model 221 with 642.8 engine:

AdBlue relay supply ®.

 –
77 Advanced sound system:

Sound amplifier (from 2009).

 50
78 S 65 AMG with 275 engine:

Fan relay (from 2009 onwards);

Valid on 221 model with 642.8 engine:

AdBlue ® relay power supply (from 2009).

 25
S 400 Hybrid, CL 63 AMG with 157, 278 engine:

Charge air cooler circulation pump (from 2009 onwards).

 15
79 Alarm siren with additional battery 7,5
80 C216:

Left door controller;

W221:

Left front door controller.

 40
81 C216:

Rear control unit

 30
W221:

Left-hand rear door control unit

 40
82 C216:

Rear control unit

 30
W221:

Left-hand rear door control unit

 40
83 Intelligent servo module for DIRECT SELECT 40
84 Advanced sound system:

Digital sound processor (from 2009)

 20
85 Valid for AMG:

Illuminated door sill trims (from 2009).

 10
86 – –
87 – –
88 – –
89 – –
90 Stationary heater:

STH heater (model 216);

STH or HB heater (model 221).

 20
91 Stationary heater:

STH radio remote control receiver;

S 400 Hybrid:

SAM front control unit with fuse and relay module.

 5
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Rear fuse and relay box

Mercedes-Benz S w221 – fuse box diagram – rear compartment
No. Description Amps [A]
115 Heated rear window 50
116 Valid for engines 157, 275, 278:

Charge air cooler circulation pump;

Applies to 156 engine:

Engine coolant circulation pump;

S 400 Hybrid:

Power electronic circulation pump 2.

 10
117 Rear cigar lighter 15
118 Valid for engine 272, 273, 642:

Fuel pump (up to 2008);

Valid for 221 model with 629, 642 engine:

Fuel pump (from 2009 onwards).

 30
S 400 Hybrid:

Power electronic circulation pump 1;

Valid for model 642.8 and engine 651 from 1.6.11 onwards:

Compressor refrigerant soda with magnet.

 15
119 Central control unit at the front 7,5
120 – –
121 Audio Tuner Control Unit 10
122 COMAND control unit 7,5
123 W221:

Reversible right front emergency voltage retractor

 40
124 W221:

Left front reversible emergency voltage retractor

 40
125 until 31.5.09:

Control unit for voice control system (VCS)

 5
126 Hanging control panel control unit 25
127 Lumbar Pump (from 2009);

Pneumatic multi-contour seat pump (left/right multi-contour seat);

Pneumatic dynamic seat control pump (dynamic multi-contour left and right seat).

 30
128 Valid for 275 engines (until 2008):

Fuel pump control unit;

Valid for 156, 157, 272, 273, 275, 276, 278, 642 engine (from 2009):

Fuel pump control unit.

 25
129 until 2008 :

Control panel control unit (sloping and sliding roof
from Glass);

as of 2009:

UPCI (Universal Portable Cell Phone Interface) control unit.

 25
130 Electric Parking Brake Controller 30
131 Rear Window Antenna Amplifier Module 7,5
133 Trailer recognition control unit;

Reversing camera (from 1.9.10).

 15
134 Plug socket 15
135 Park Assist; until 2008:

Radar Sensor Control Unit (SGR);

Front short range radar unit;

Rear short-range radar unit;

DISTRONIC PLUS until 31.8.10 or Blind Spot Assist or Adaptive Cruise Control Plus Light:

Radar Sensor Control Unit (SGR) (from 2009);

PARKTRONIC parking assistant or Exclusive:

PTS control unit.

 7,5
136 Valid for the 221 model with 642.8 engine:

AdBlue control unit ®.

 7,5
137 Reversing camera (from 1.9.10) 7,5
138 Navigation Processor (since 2009) (until 31.8.10);

Emergency call system control unit (from 2009);

Japanese version:

TV/tuner connector (from 2009).

 5
139 Rear refrigerator 15
140 Rear cigarette lighter with ashtray lighting connector;

115 V socket (from 2009).

 15
141 Reversing chamber control unit 5
142 Parktronic system control unit (PTS);

Distronic Plus:

Radar sensor control unit (SGR);

Valid as of 1.9.10 for DISTRONIC PLUS and Active Blind Spot Assist or Active Lane Keeping Assist:

Control unit for the video system and radar sensor.

 7,5
143 Rear seat controller 25
144 Rear seat controller 25
145 Trailer recognition control unit (until 2008);

Trailer hitch socket (13-pin) (from 2009).

 20
146 Trailer recognition control unit 25
147 until 2008:

TLC Control Unit [HDS] (remote trunk locking)

 30
148 until 2008 ..:

CTEL Universal Portable Control Unit (UPCI [UHI])

 7,5
as of 2009:

Sliding panoramic sunroof, perimeter 30 connection sleeve

 25
149 until 2008:

Control unit for the voice control system (VCS [SBS])

 5
as of 2009:

Panoramic sliding roof control module

 25
150 TV combination tuner (analog / digital);

Japanese version:

TV connector / tuner (from 2009).

 7,5
151 W221; until 2008:

Electric parking brake controller

 25
W221; from 2009:

Trailer recognition control unit

 20
152 W221:

Rear window antenna amplifier module

 7,5
115 V socket:

DC / AC converter control unit

 25
Relay
M Terminal 15 relay
N Terminal 15R Relay
O Power socket relay
P. Heated Rear Window Relay
Q Valid for engine 156, 157, 275, 278, 629:

Relay recirculation pump

S 400 Hybrid:

Valid for model 221.095 / 195:

Power electronics circulation pump relay 2
R Cigarette Lighter Relay
S Fuel Pump Relay
Valid for engine 642.8 and engine 651 from 1.6.11 onwards:

Connected via the fuel pump:

Magnetic coupling of the refrigerant compressor;

S 400 Hybrid:

Electronic power circulating pump relay 1.
See also  Mercedes-Benz E-Class W212 (2009-2016) - fuse box

Internal Prebox (until 2008)

Mercedes-Benz S – W221 – Fuse box diagram – internal fuse box
No. Description Amps [A]
1 Starter 400
2 Not applicable to the 642 engine:

Alternator

 150
Valid for engine 642:

Alternator

 200
3 – 150
4 AAC with integrated additional fan motor control 150
5 Valid for engine 642:

PTC heater booster

 200
6 SAM front control unit with fuse and relay module 200
7 ESP Control Unit 40
8 ESP Control Unit 25
9 SAM front control unit with fuse and relay module 20
10 Vehicle Power Control Unit 7,5

Prebox internal (from 2009)

Mercedes-Benz S – W221 – Fuse box diagram – internal fuse box
No. Description Amps [A]
3 Rear SAM control unit with fuse and relay module 150
4 Function ECO start/stop:

Relay functions ECO start/stop;

S 400 Hybrid:

Controller with dc/dc converter;

Heated windshield:

Heated Windshield.

 150
5 Valid for model 221 (electrical installation in rental vehicle):

Special multifunction vehicle control unit (SVMCU [MSS]).

 40
S 400 Hybrid:

Vacuum Pump

 80
6 Instrument panel fuse box on the right 80
7 Valid for 221 model with 629, 642, 651 engine:

PTC heater;

Valid for model 221

(Initial installation Electricity for rental vehicle):

Special multifunctional vehicle control unit (SVMCU [MSS]).

 150
8 SAM front control unit with fuse and relay module 80
9 Left instrument panel fuse box 80
10 Rear SAM control unit with fuse and relay module 150

Engine compartment pre-fuse box (until 2008).

Mercedes-Benz S – w221 – fuse box diagram – engine compartment pre-fuse box
No. Description Amps [A]
1 Front fuse box
(through the on-board mains pyrofuse)		 –
2 Control unit for the heated windscreen 125
3 Instrument panel fuse box on the right 80
4 Rear SAM control unit with fuse and relay module 200
5 Special multifunction control unit for vehicles (SVMCU [MSS]) 100
6 Rear SAM control unit with fuse and relay module 150
7 SAM front control unit with fuse and relay module 100
8 Left instrument panel fuse box 80
9 SAM front control unit with fuse and relay module 5
10 C216:

Control unit for the emergency call system

 5

Engine compartment pre-fuse box (from 2009).

Mercedes-Benz S – w221 – fuse box diagram – engine compartment pre-fuse box
No. Description Amps [A]
2 Alternator 460
3 Electro-hydraulic power steering;

Valid for 221 model with 629, 642 engine:

Light output phase.

 150
4 Prebox inside (not used) –
5 AAC with integrated additional fan motor control 100
6 SAM front control unit with fuse and relay module 150
7 ESP Control Unit S 400 Hybrid:

Brake system control unit with energy recovery.

 40
8 ESP control unit;

S 400 Hybrid:

Brake system control unit with energy recovery.

 25
9 SAM front control unit with fuse and relay module 25
10 Reservation –

AdBlue Fuse Block

Mercedes-Benz S – W221 – Fuse box diagram – AdBlue fuse block
No. Description Amps[A]
A AdBlue control unit 7,5
B Heating circuit 1 20
C Heating circuit 1 20
D Reservation –

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